Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The eIF3a translational control axis in the Wnt/β-catenin signaling pathway and colon tumorigenesis.

Cancer letters - 28 Nov 2024

Dong Zizheng, Ojha Anuj, Barlow Lincoln, Luo Liyun, Liu Jing-Yuan, Zhang Jian-Ting

Abstract excerpt

Translational initiation in protein synthesis is an important regulatory step in gene expression and its dysregulation may result in diseases such as cancer. Translational control by eIF4E/4E-BP has been well studied and contributes to mTOR signaling in various biological processes. Here, we report a novel translational control axis in the Wnt/β-catenin signaling pathway in colon tumorigenesis by eIF3a, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli Protein
Share to beta Catenin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinogenesis

Share to Cell Transformation, Neoplastic

Share to Colonic Neoplasms

Share to Eukaryotic Initiation Factor-3

Share to Protein Biosynthesis

Share to Wnt Signaling Pathway

Source

Open in PubMed Open full text

Identifiers

PMID: 39413959
DOI: 10.1016/j.canlet.2024.217303
PMCID: PMC11646415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The eIF3a translational control axis in the Wnt/β-catenin signaling pathway and colon tumorigenesis.PMID 39413959Read ↗

Targeting Protein Synthesis in Colorectal CancerSemantic proximity Read ↗

Targeting the eIF4F translation initiation complex for cancer therapySemantic proximity Read ↗

Eukaryotic translation initiation factor 5A in the pathogenesis of cancers (Review)Semantic proximity Read ↗

RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancerSemantic proximity Read ↗

Computational inference of eIF4F complex function and structure in human cancersSemantic proximity Read ↗

Translation initiation: a critical signalling node in cancer.Semantic proximity Read ↗

Maintenance of p-eIF2α levels by the eIF2B complex is vital for colorectal cancer.Semantic proximity Read ↗

Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity.Semantic proximity Read ↗

MicroRNA, SND1, and alterations in translational regulation in colon carcinogenesisSemantic proximity Read ↗

Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer TherapySemantic proximity Read ↗

eIF3 targets cell-proliferation messenger RNAs for translational activation or repression.Semantic proximity Read ↗

Translation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.