Article
m6Acancer-Net: Identification of m6A-mediated cancer driver genes from gene-site heterogeneous network.
Methods (San Diego, Calif.) - 1 Jul 2022
Ma Qianqian, Zhang Shao-Wu, Zhang Song-Yao
Abstract excerpt
N6-methyladenosine (m6A) is the most abundant eukaryotic modification internal mRNA, which plays the crucial roles in the occurrence and development of cancer. However, current knowledge about m6A-mediated functional circuit and key genes targeted by m6A methylation in cancer is mostly elusive. Thus, here we proposed a novel network-based approach (called m6Acancer-Net) to identify m6A-mediated driver genes and...
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