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m6A-TSHub: Unveiling the Context-specific m6A Methylation and m6A-affecting Mutations in 23 Human Tissues.

Genomics, proteomics & bioinformatics - 1 Aug 2023

Song Bowen, Huang Daiyun, Zhang Yuxin, Wei Zhen, Su Jionglong, Pedro de Magalhães João, Rigden Daniel J, Meng Jia, Chen Kunqi

Abstract excerpt

As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs (lncRNAs), N6-methyladenosine (m6A) RNA methylation has been shown to participate in essential biological processes. Recent studies have revealed the distinct patterns of m6A methylome across human tissues, and a major challenge remains in elucidating the tissue-specific presence and circuitry of m6A methylation. We present here a...

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PMID: 36096444
DOI: 10.1016/j.gpb.2022.09.001
PMCID: PMC10787194

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