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Article

Parallel evolution of fluconazole resistance and tolerance in Candida glabrata.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Zheng Lijun, Xu Yi, Wang Chen, Dong Yubo, Guo Liangsheng

Abstract excerpt

Introduction: With the growing population of immunocompromised individuals, opportunistic fungal pathogens pose a global health threat. Candida species, particularly C. albicans and non-albicans Candida species such as C. glabrata, are the most prevalent pathogenic fungi. Azoles, especially fluconazole, are widely used therapeutic options. Objective: This study investigates how C. glabrata adapts to fluconazole,...

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Identifiers

PMID: 39397866
DOI: 10.3389/fcimb.2024.1456907
PMCID: PMC11466938

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