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Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans

11 Nov 2020

Abstract excerpt

Candida albicans is an important human pathogen and a major concern in intensive care units around the world. C. albicans infections are associated with a high mortality despite the use of antifungal treatments. One of the causes of therapeutic failures is the acquisition of antifungal resistance by mutations in the C. albicans genome. Fluconazole (FLC) is one of the most widely used antifungal and mechanisms of...

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PMID: 33262748
DOI: 10.3389/fmicb.2020.591140

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