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Multifactorial Mechanisms of Tolerance to Ketoconazole in Candida albicans

23 Jun 2021

Abstract excerpt

Due to the ever-expanding range of invasive medical procedures and treatments, invasive fungal infections now pose a serious global threat to many people living in an immunocompromised status. Like humans, fungi are eukaryotic, which significantly limits the number of unique antifungal targets; the current arsenal of antifungal agents is limited to just three frontline drug classes. Additional treatment...

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PMID: 34160280
DOI: 10.1128/spectrum.00321-21

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