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Article

Genotypic, phenotypic, and proteomic characterization of Candida glabrata during sequential fluconazole exposure.

Journal of investigative and clinical dentistry - 1 May 2011

Samaranayake Yuthika Hemamala, Cheung Becky Pik Ki, Yau Joyce Yick Yee, Yeung Kim Wai, Samaranayake Lakshman Perera

Abstract excerpt

AIM: Candida glabrata is a major pathogen in humans known to be intrinsically resistant to fluconazole. However, genotypic, phenotypic, and proteomic changes associated with reduced susceptibility to fluconazole are not properly understood. The aim of this study was to observe specific phenotypic, chromosomal, and proteomic alterations in a Candida glabrata strain sequentially exposed to fluconazole. METHODS:...

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Source

Identifiers

PMID: 25426605
DOI: 10.1111/j.2041-1626.2011.00044.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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