Article

Fungal resistance to echinocandins and the MDR phenomenon in Candida glabrata

2018-08-17

Abstract excerpt

Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures prior to and during antifungal treatment. Out of all the medically relevant Candida species, C. glabrata has emerged as a leading cause of azole, echinocandin, and multidrug (MDR: azole + echinocandin) adaptive resistance. Neither mechanism of resistance is intrinsic to C. glabrata, since stable g...

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Literature Corpus work: 50c56cc5-8bdc-5da3-8382-db9d2b9ac8f1
DOI: 10.20944/preprints201808.0306.v1

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