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Genome sequencing analysis of the pncA, rpsA and panD genes responsible for pyrazinamide resistance of Mycobacterium tuberculosis from Indonesian isolates.

Tropical medicine & international health : TM & IH - 1 Nov 2024

Rukmana Andriansjah, Nurfadillah Mifa, Gozali Cynthia, Kiranasari Ariyani

Abstract excerpt

BACKGROUND: Developing the most suitable treatment against tuberculosis based on resistance profiles is imperative to effectively cure tuberculosis patients. Whole-genome sequencing is a molecular method that allows for the rapid and cost-effective detection of mutations in multiple genes associated with anti-tuberculosis drug resistance. This sequencing approach addresses the limitations of culture-based...

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PMID: 39397216
DOI: 10.1111/tmi.14051

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