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Article

TERT promoter mutations and survival outcomes in adult-type granulosa cell tumors.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Aug 2025

Brodsky Allison L, Flores Legarreta Alejandra, Fellman Bryan M, Glassman Deanna, How Jeffrey, Vuttaradhi Veena, Sood Anil K, Ramondetta Lois Michelle, Gershenson David, Hillman R Tyler

Abstract excerpt

OBJECTIVES: To evaluate survival outcomes among patients with adult-type granulosa cell tumors who have telomerase reverse transcriptase (TERT) promoter mutations. METHODS: This is a retrospective cohort study using the MD Anderson Rare Gynecologic Malignancy Registry. Patients with adult granulosa cell tumors who underwent molecular testing for TERT promoter and FOXL2 c.C402G mutations were included. We used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39395821
DOI: 10.1136/ijgc-2024-005837
PMCID: PMC12228831

Genes

TERT
FOXL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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