Article
Clinical and genetic analysis of recurrent adult-type granulosa cell tumor of the ovary: Persistent preservation of heterozygous c.402C>G FOXL2 mutation.
PloS one - 1 Jan 2017
Yanagida Satoshi, Anglesio Michael S, Nazeran Tayyebeh M, Lum Amy, Inoue Momoko, Iida Yasushi, Takano Hirokuni, Nikaido Takashi, Okamoto Aikou, Huntsman David G
Abstract excerpt
BACKGROUND: Adult-type granulosa cell tumors of the ovary (aGCTs) are rare tumors that represent 2-5% of ovarian malignancies. The prognosis of this tumor is favorable, and it is characterized by slow progression. 10-30% of these tumors recur after 4-7 years of the primary surgery and the 5-year survival rate from the first recurrence is 55%, for the incompletely resected patients. At this time, complete...
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