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Predicting recurrence in adult granulosa cell tumors: the role of Ki67, p53, and TERT mutations.

Archives of gynecology and obstetrics - 1 Feb 2025

Bayram Aysel, Bagbudar Sidar, Yılmaz İsmail, Sozen Hamdullah, Minareci Yağmur, Altay Ali Yılmaz, Altunbas Sabire Aslı, Yavuz Ekrem, Onder Semen

Abstract excerpt

PURPOSE: Adult granulosa cell tumors (aGCTs) are a rare type of ovarian malignancy. While most aGCTs have an indolent course, up to 25% experience recurrence. Identifying markers for disease recurrence is crucial for optimal management. METHODS: Our study consisted of a total of 55 patients, comprising primary non-recurrent aGCTs (n = 30), aGCT recurrences without corresponding primary tumors (n = 19), and...

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Share to Ki-67 Antigen
Share to Neoplasm Recurrence, Local

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Granulosa Cell Tumor

Share to Immunohistochemistry

Share to Ovarian Neoplasms

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Source

Identifiers

PMID: 39688684
DOI: 10.1007/s00404-024-07888-2

Genes

TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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