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Article

Interactions between Polygenic Risk of Obesity and Dietary Factors on Anthropometric Outcomes: A Systematic Review and Meta-Analysis of Observational Studies.

The Journal of nutrition - 1 Dec 2024

Han Hannah Yang, Masip Guiomar, Meng Tongzhu, Nielsen Daiva E

Abstract excerpt

BACKGROUND: Diet is an important determinant of health and may moderate genetic susceptibility to obesity, but meta-analyses of available evidence are lacking. OBJECTIVES: This study aimed to systematically review and meta-analyze evidence on the moderating effect of diet on genetic susceptibility to obesity, assessed with polygenic risk scores (PRS). METHODS: A systematic search was conducted using MEDLINE,...

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Anthropometry
Body Mass Index
Diet
Genetic Predisposition to Disease
Multifactorial Inheritance

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PMID: 39393497
DOI: 10.1016/j.tjnut.2024.10.014
PMCID: PMC11662244

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