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Article

Polygenic Risk and Nutrient Intake Interactions on Obesity Outcomes: A Systematic Review and Meta-Analysis of Observational Studies.

Obesity reviews : an official journal of the International Association for the Study of Obesity - 1 Sept 2025

Masip Guiomar, Han Hannah Yang, Meng Tongzhu, Nielsen Daiva E

Abstract excerpt

BACKGROUND: Diet is an important determinant of body weight and may modulate genetic susceptibility to obesity. OBJECTIVE: This systematic review and meta-analysis aimed to synthesize evidence related to interactions between polygenic risk and nutrient intakes on obesity outcomes. METHODS: MEDLINE, EMBASE, Web of Science, and Cochrane Library were systematically searched to identify observational studies that...

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Body Mass Index
Diet
Dietary Fats
Energy Intake
Multifactorial Inheritance

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PMID: 40375759
DOI: 10.1111/obr.13941
PMCID: PMC12318916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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