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Article

Analysis of the Interaction between Polygenic Risk Score and Calorie Intake in Obesity in the Korean Population.

Lifestyle genomics - 1 Jan 2021

Lee Won-Jun, Lim Ji Eun, Jung Hae Un, Kang Ji-One, Park Taesung, Won Sungho, Rhee Sang Youl, Kim Mi Kyung, Kim Yeon-Jung, Oh Bermseok

Abstract excerpt

INTRODUCTION: Obesity results from an imbalance in the intake and expenditure of calories that leads to lifestyle-related diseases. Although genome-wide association studies (GWAS) have revealed many obesity-related genetic factors, the interactions of these factors and calorie intake remain unknown. This study aimed to investigate interactions between calorie intake and the polygenic risk score (PRS) of BMI....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33302275
DOI: 10.1159/000511333

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