Article
The genetic architecture of the association between eating behaviors and obesity: combining genetic twin modeling and polygenic risk scores.
The American journal of clinical nutrition - 1 Oct 2020
Masip Guiomar, Silventoinen Karri, Keski-Rahkonen Anna, Palviainen Teemu, Sipilä Pyry N, Kaprio Jaakko, Bogl Leonie H
Abstract excerpt
BACKGROUND: Obesity susceptibility genes are highly expressed in the brain suggesting that they might exert their influence on body weight through eating-related behaviors. OBJECTIVES: To examine whether the genetic susceptibility to obesity is mediated by eating behavior patterns. METHODS: Participants were 3977 twins (33% monozygotic, 56% females), aged 31-37 y, from wave 5 of the FinnTwin16 study. They...
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