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Article

Exploration of protein and genetic targets causing atrioventricular block: mendelian-randomization analyses based on eQTL data and pQTL data.

BMC cardiovascular disorders - 1 Oct 2024

Wang Tongyu, Ma Peipei, Wang Xiaofang, Xia Yunlong

Abstract excerpt

BACKGROUND: Atrioventricular block (AVB) is a heterogeneous group of arrhythmias. AVB can lead to sudden arrest of the heart and subsequent syncope or sudden cardiac death. Few scholars have investigated the underlying molecular mechanisms of AVB. Finding molecular markers can facilitate understanding of AVB and exploration of therapeutic targets. METHODS: Two-sample Mendelian randomization (MR) analysis was...

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Identifiers

PMID: 39354406
DOI: 10.1186/s12872-024-04209-y
PMCID: PMC11443760

Genes

ABO
DNAJC30

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