Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between plasma proteome and pulmonary heart disease: A two-stage Mendelian randomization analysis.

The clinical respiratory journal - 1 Jun 2024

Li Shiyang, Ding Haifeng, Li Qi, Zeng Xiaobin, Zhang Yanyu, Lai Chengyi, Xie Xiaoshuang, Tang Yongjiang, Lan Jianjun

Abstract excerpt

Pulmonary heart disease (PHD) involves altered structure and function of the right ventricle caused by an abnormal respiratory system that causes pulmonary hypertension. However, the association between changes in plasma proteomics and PHD remains unclear. Hence, we aimed to identify causal associations between genetically predicted plasma protein levels and PHD. Mendelian randomization was performed to test the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ABO Blood-Group System
Share to Blood Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Proteome

Share to Proteomics

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 38830831
DOI: 10.1111/crj.13775
PMCID: PMC11147680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between plasma proteome and pulmonary heart disease: A two-stage Mendelian randomization analysis.PMID 38830831Read ↗

Identification and genetic validation of potential therapeutic targets for pulmonary hypertension through multi-omics causal inference.Semantic proximity Read ↗

Proteome-wide Mendelian randomization identifies candidate causal proteins for cardiovascular diseasesSemantic proximity Read ↗

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failureSemantic proximity Read ↗

Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failureSemantic proximity Read ↗

Proteome-wide Mendelian randomization analyses to identify potential therapeutic targets for lung function and respiratory diseaseSemantic proximity Read ↗

Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome.Semantic proximity Read ↗

Identification of Emerging Drug Targets for Pulmonary Functions Through Mendelian Randomization Analysis of the Plasma ProteomeSemantic proximity Read ↗

Cross-population proteome-wide mendelian randomization study identifies likely causal proteins for cardiovascular diseases.Semantic proximity Read ↗

Identification of therapeutic targets for 18 clinical diseases by integrating human plasma proteome with genomeSemantic proximity Read ↗

Comprehensive mendelian randomization analysis of plasma proteomics to identify new therapeutic targets for the treatment of coronary heart disease and myocardial infarctionSemantic proximity Read ↗

Systematic Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinomaSemantic proximity Read ↗

Plasma genome-wide mendelian randomization identifies potentially causal genes in idiopathic pulmonary fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.