Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MethylGenotyper: Accurate Estimation of SNP Genotypes and Genetic Relatedness from DNA Methylation Data.

Genomics, proteomics & bioinformatics - 13 Sept 2024

Jiang Yi, Qu Minghan, Jiang Minghui, Jiang Xuan, Fernandez Shane, Porter Tenielle, Laws Simon M, Masters Colin L, Guo Huan, Cheng Shanshan, Wang Chaolong

Abstract excerpt

Epigenome-wide association studies (EWAS) are susceptible to widespread confounding caused by population structure and genetic relatedness. Nevertheless, kinship estimation is challenging in EWAS without genotyping data. Here, we proposed MethylGenotyper, a method that for the first time enables accurate genotyping at thousands of single nucleotide polymorphisms (SNPs) directly from commercial DNA methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Genome-Wide Association Study

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 39353864
DOI: 10.1093/gpbjnl/qzae044
PMCID: PMC12016561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MethylGenotyper: Accurate Estimation of SNP Genotypes and Genetic Relatedness from DNA Methylation Data.PMID 39353864Read ↗

Genome-wide methylation data mirror ancestry informationSemantic proximity Read ↗

Genome-wide methylation data mirror ancestry information.Semantic proximity Read ↗

Genomic and phenomic insights from an atlas of genetic effects on DNA methylationSemantic proximity Read ↗

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.Semantic proximity Read ↗

Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traitsSemantic proximity Read ↗

JEM: A joint test to estimate the effect of multiple genetic variants on DNA methylation.Semantic proximity Read ↗

A pooling-based approach to mapping genetic variants associated with DNA methylation.Semantic proximity Read ↗

Genetic control of DNA methylation is largely shared across European and East Asian populations.Semantic proximity Read ↗

Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping.Semantic proximity Read ↗

Gene-methylation interactions: discovering region-wise DNA methylation levels that modify SNP-associated disease risk.Semantic proximity Read ↗

Gene, Environment and Methylation (GEM): a tool suite to efficiently navigate large scale epigenome wide association studies and integrate genotype and interaction between genotype and environment.Semantic proximity Read ↗

Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.