Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Concurrent analysis of genome and transcriptome in one single cell.

BMC research notes - 16 Sept 2024

Heid Johanna, Cutler Ronald, Lee Moonsook, Vijg Jan, Maslov Alexander Y

Abstract excerpt

Thus far, multiple techniques for single cell analysis have been developed, yet we lack a relatively simple tool to assess DNA and RNA from the same cell at whole-transcriptome and whole-genome depths. Here we present an updated method for physical separation of cytoplasmic RNA from the nuclei, which allows for simultaneous studies of DNA and RNA from the same single cell. The method consists of three steps-(1)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleus
Share to DNA
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Mutation

Share to Single-Cell Analysis

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 39285281
DOI: 10.1186/s13104-024-06927-0
PMCID: PMC11403997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Concurrent analysis of genome and transcriptome in one single cell.PMID 39285281Read ↗

Concurrent analysis of genome and transcriptome in one single cellSemantic proximity Read ↗

Applications of Single-Cell Sequencing for Multiomics.Semantic proximity Read ↗

Single cell genomics: advances and future perspectives.Semantic proximity Read ↗

Analyzing somatic mutations by single-cell whole-genome sequencing.Semantic proximity Read ↗

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI).Semantic proximity Read ↗

Separation and parallel sequencing of the genomes and transcriptomes of single cells using G&T-seq.Semantic proximity Read ↗

Single-Cell GenomicsSemantic proximity Read ↗

Advances and Applications of Single-Cell Sequencing TechnologiesSemantic proximity Read ↗

Integrated sequencing of exome and mRNA of large-sized single cells.Semantic proximity Read ↗

Multi-omic profiling of transcriptome and DNA methylome in single nuclei with molecular partitioningSemantic proximity Read ↗

Capsule-Based Single-Cell Genome SequencingSemantic proximity Read ↗

Accurate identification of single-nucleotide variants in whole-genome-amplified single cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.