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Article

Concurrent analysis of genome and transcriptome in one single cell

2023-08-03

Abstract excerpt

Thus far, multiple techniques for single cell analysis have been developed, yet we lack a relatively simple tool to assess DNA and RNA from the same cell at whole-transcriptome and whole-genome depths. Here we present an updated method for physical separation of cytoplasmic RNA from the nuclei, which allows for simultaneous studies of DNA and RNA from the same single cell. The method consists of three steps – 1) i...

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Identifiers and source

Literature Corpus work
328b5e61-8615-559d-8767-a5b303b1e0d3
DOI
10.21203/rs.3.rs-3186428/v1
Open publication

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