Article
Differences in mutations across tumour sizes in clear-cell renal cell carcinoma.
BJU international - 1 Feb 2025
Monda Steven M, Carney Benjamin W, May Allison M, Gulati Shuchi, Salami Simpa S, Chandrasekar Thenappan, Keller Evan T, Huebner Nicolai A, Palapattu Ganesh S, Dall'Era Marc A
Abstract excerpt
OBJECTIVE: To assess the distribution of key mutations across tumour sizes in clear-cell renal cell carcinoma (ccRCC), and secondarily to examine the prognostic impact of aggressive mutations in smaller ccRCCs. PATIENT AND METHODS: The distribution of mutations (VHL, PBRM1, SETD2, BAP1 and CDKN2A loss) across tumour sizes was assessed in 1039 ccRCCs treated with nephrectomy in cohorts obtained from the Tracking...
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- Humans
- Kidney Neoplasms
- Carcinoma, Renal Cell
- Mutation
- Male
- Female