Article
Characterizing recurrent and lethal small renal masses in clear cell renal cell carcinoma using recurrent somatic mutations.
Urologic oncology - 1 Jan 2019
Manley Brandon J, Reznik Ed, Ghanaat Mazyar, Kashan Mahyar, Becerra Maria F, Casuscelli Jozefina, Tennenbaum Daniel, Redzematovic Almedina, Carlo Maria I, Sato Yusuke, Arcila Maria, Voss Martin H, Feldman Darren R, Motzer Robert J, Russo Paul, Coleman Jonathan, Hsieh James J, Hakimi Ari A
Abstract excerpt
INTRODUCTION: Small renal masses (SRMs) with evidence of clear cell renal cell carcinoma (ccRCC) are understudied. Current algorithms for the management of SRMs include surgical resection, ablation, and active surveillance. We sought to identify genomic biomarkers that could potentially refine the management of ccRCC in SRMs, especially in patients being evaluated for active surveillance. METHODS: We identified...
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