Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma.

doi:10.1016/j.euf.2016.06.015

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Article

Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma.

European urology focus - 1 Oct 2017

Manley Brandon John, Zabor Emily C, Casuscelli Jozefina, Tennenbaum Daniel M, Redzematovic Almedina, Becerra Maria F, Benfante Nicole, Sato Yusuke, Morikawa Teppei, Kume Haruki, Fukayama Masashi, Homma Yukio, Ogawa Seishi, Arcila Maria E, Voss Martin H, Feldman Darren R, Coleman Jonathan A, Reuter Victor E, Motzer Robert J, Russo Paul, Hsieh James J, Hakimi A Ari

Abstract excerpt

BACKGROUND: Analyses of associations between clinicopathologic outcomes and recurrent somatic mutations in clear cell renal cell carcinoma (ccRCC) have been limited to individual cohorts. OBJECTIVE: To define clinicopathologic associations between specific mutations and ccRCC disease characteristics. DESIGN, SETTING, AND PARTICIPANTS: DNA sequencing data were pooled from three collaborative genomic cohorts...

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Identifiers

PMID: 28753773
DOI: 10.1016/j.euf.2016.06.015
PMCID: PMC5650556

Genes

BAP1
SETD2

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