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Article

Multi-omics Mendelian randomization integrating GWAS, eQTL and pQTL data revealed GSTM4 as a potential drug target for migraine.

The journal of headache and pain - 22 Jul 2024

Sun Xinyue, Chen Bohong, Qi Yi, Wei Meng, Chen Wanying, Wu Xiaoyu, Wang Qingfan, Li Jiahao, Lei Xiangyu, Luo Guogang

Abstract excerpt

INTRODUCTION: Migraine, as a complex neurological disease, brings heavy burden to patients and society. Despite the availability of established therapies, existing medications have limited efficacy. Thus, we aimed to find the drug targets that improve the prognosis of migraine. METHOD: We used Mendelian Randomization (MR) and Summary-data-based MR (SMR) analyses to study possible drug targets of migraine by...

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Source

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Identifiers

PMID: 39039470
DOI: 10.1186/s10194-024-01828-w
PMCID: PMC11265128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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