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Article

Population suppression with dominant female-lethal alleles is boosted by homing gene drive.

BMC biology - 11 Sept 2024

Zhu Jinyu, Chen Jingheng, Liu Yiran, Xu Xuejiao, Champer Jackson

Abstract excerpt

BACKGROUND: Methods to suppress pest insect populations using genetic constructs and repeated releases of male homozygotes have recently been shown to be an attractive alternative to older sterile insect techniques based on radiation. Female-specific lethal alleles have substantially increased power, but still require large, sustained transgenic insect releases. Gene drive alleles bias their own inheritance to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39256812
DOI: 10.1186/s12915-024-02004-x
PMCID: PMC11389273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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