Article
Confinement of gene drive systems to local populations: a comparative analysis.
Journal of theoretical biology - 7 Feb 2012
Marshall John M, Hay Bruce A
Abstract excerpt
Mosquito-borne diseases such as malaria and dengue fever pose a major health problem through much of the world. One approach to disease prevention involves the use of selfish genetic elements to drive disease-refractory genes into wild mosquito populations. Recently engineered synthetic drive systems have provided encouragement for this strategy; but at the same time have been greeted with caution over the...
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