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Article

RNA Splicing Events in Circulation Distinguish Individuals With and Without New-onset Type 1 Diabetes

10 Sept 2024

Abstract excerpt

CONTEXT: Alterations in RNA splicing may influence protein isoform diversity that contributes to or reflects the pathophysiology of certain diseases. Whereas specific RNA splicing events in pancreatic islets have been investigated in models of inflammation in vitro, how RNA splicing in the circulation correlates with or is reflective of type 1 diabetes (T1D) disease pathophysiology in humans remains unexplored....

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Identifiers

PMID: 39252615
DOI: 10.1210/clinem/dgae622

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