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Article

Polygenic risk of high LDL cholesterol and ischemic heart disease in the general population.

Atherosclerosis - 1 Oct 2024

Eyrich Tim Møller, Dalila Nawar, Christoffersen Mette, Tybjærg-Hansen Anne, Stender Stefan

Abstract excerpt

BACKGROUND AND AIMS: We tested the association of polygenic risk scores (PRS) for low-density lipoprotein cholesterol (LDL-C) and coronary artery disease (CAD) with LDL-C and risk of ischemic heart disease (IHD) in the Danish general population. METHODS: We included a total of 21,485 individuals from the Copenhagen General Population Study and Copenhagen City Heart Study. For everyone, LDL-PRS and CAD-PRS were...

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PMID: 39244851
DOI: 10.1016/j.atherosclerosis.2024.118574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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