Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VEGF and ELAVL1/HuR protein levels are increased in dry and wet AMD patients. A new tile in the pathophysiologic mechanisms underlying RPE degeneration?

30 Aug 2024

Abstract excerpt

Age-related macular degeneration (AMD) is a common retinal pathology characterized by degeneration of macula’s retinal pigment epithelium (RPE) and photoreceptors, visual impairment, or loss. Compared to wet AMD, dry AMD is more common, but lacks cures; therefore, identification of new potential therapeutic targets and treatments is urgent. Increased oxidative stress and declining antioxidant, detoxifying systems...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics, phytochemicals, and oxidative stress
Share to Retinal Diseases and Treatments
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39216841
DOI: 10.1016/j.phrs.2024.107380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 12 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VEGF and ELAVL1/HuR protein levels are increased in dry and wet AMD patients. A new tile in the pathophysiologic mechanisms underlying RPE degeneration?PMID 39216841Read ↗

Central Role of Oxidative Stress in Age-Related Macular Degeneration: Evidence from a Review of the Molecular Mechanisms and Animal ModelsSemantic proximity Read ↗

Regulatory factors of Nrf2 in age-related macular degeneration pathogenesisSemantic proximity Read ↗

Age-related driving mechanisms of retinal diseases and neuroprotection by transcription factor EB-targeted therapySemantic proximity Read ↗

AAV-NRF2 protects retinal and choroidal vasculature in a GDF15-dependent manner in an oxidative damage model of AMDSemantic proximity Read ↗

AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative DamageSemantic proximity Read ↗

The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration PathologySemantic proximity Read ↗

Not All Stressors Are Equal: Mechanism of Stressors on RPE Cell DegenerationSemantic proximity Read ↗

ER Stress and Mitochondrial Perturbations Regulate Cell Death in Retinal Detachment: Exploring the Role of HIF1αSemantic proximity Read ↗

Oxidative Stress in Age-Related Macular Degeneration: Nrf2 as Therapeutic TargetSemantic proximity Read ↗

LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target.Semantic proximity Read ↗

Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptorsSemantic proximity Read ↗

Disruptions of Autophagy in the Rat Retina with Age During the Development of Age-Related-Macular-Degeneration-like RetinopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.