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Not All Stressors Are Equal: Mechanism of Stressors on RPE Cell Degeneration

19 Nov 2020

Abstract excerpt

Age-related macular degeneration (AMD) is a major cause of irreversible blindness among the elderly population. Dysfunction and degeneration of the retinal pigment epithelial (RPE) layer in the retina underscore the pathogenesis of both dry and wet AMD. Advanced age, cigarette smoke and genetic factors have been found to be the prominent risk factors for AMD, which point to an important role for oxidative stress...

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PMID: 33330470
DOI: 10.3389/fcell.2020.591067

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