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Article

Identification of breast cancer-associated PIK3CA H1047R mutation in blood circulation using an asymmetric PCR assay.

PloS one - 1 Jan 2024

Thao Dinh Thi, Thanh Nguyen Phu, Quyen Dong Van, Khai Ly Tuan, Song Le Huu, Trung Ngo Tat

Abstract excerpt

PURPOSE: To establish a highly sensitive and specific approach for the detection of circulating PIK3CA H1047R mutation in breast cancer (BC) patients and to investigate the association between the prevalence of PIK3CA H1047R mutation and clinical presentations. METHODS: A proper blocker was designed in an allele-specific manner and optimized for PCR-based identification of the PIK3CA H1047R mutation. The...

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Identifiers

PMID: 39197004
DOI: 10.1371/journal.pone.0309209
PMCID: PMC11356436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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