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PIK3CA Mutational Profiling in a Patient Cohort with HR+/HER2- Advanced Metastatic Breast Cancer at a Tertiary Cancer Center

2023-03-29

Abstract excerpt

Common PIK3CA gene activating mutations can be found in 20–30% of all breast cancer cases, and regarded as predictive markers for therapeutic response to PI3K inhibitors. The therascreen PIK3CA mutation companion assay and the alpha-specific PI3K inhibitor, Alpelisib, are FDA-approved for selecting and treating patients with advanced PIK3CA-mutated metastatic breast cancer. The main objective behind this report wa...

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Literature Corpus work: 51c5a924-ca0e-5644-bdb1-4196617b5aa4
DOI: 10.21203/rs.3.rs-2699737/v1

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