Article

The Diagnostic Accuracy of PIK3CA Mutations by circulating tumor DNA (ctDNA) in Breast Cancer: An Individual Patient Data Meta-analysis

2022-03-21

Abstract excerpt

<h4>Background: </h4> The circulating tumor DNA (ctDNA) diagnostic accuracy for detecting Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ( PIK3CA ) mutations in breast cancer is under discussion. We aimed to compare plasma and tissue PIK3CA alterations, encompassing factors that could affect the results. Methods Two reviewers selected studies from different databases until December 2020....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3c9eec2a-65ad-50fe-a090-36418c69c282
DOI: 10.21203/rs.3.rs-1462801/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Diagnostic Accuracy of PIK3CA Mutations by circulating tumor DNA (ctDNA) in Breast Cancer: An Individual Patient Data Meta-analysisDOI 10.21203/rs.3.rs-1462801/v1Read

Diagnostic Accuracy of PIK3CA Mutation Detection by Circulating Free DNA in Breast Cancer: A Meta-Analysis of Diagnostic Test Accuracy.Semantic proximity Read

Serial Circulating Tumor DNA Identification Associated with the Efficacy and Prognosis of Neoadjuvant Chemotherapy in Breast CancerSemantic proximity Read

PIK3CA mutation detection by circulating tumor cell sequencing guides the effective PI3K inhibitor treatment of a patient with hormone receptor-positive breast cancer transformed into triple-negative breast cancer: A case report.Semantic proximity Read

Frequency and spectrum of PIK3CA somatic mutations in breast cancer.Semantic proximity Read

Survival analysis of patients with early breast cancer associated with PIK3CA mutationSemantic proximity Read

Circulating Tumor DNA Mutation Profiling Reveals Prognostic Signatures in Breast CancerSemantic proximity Read

Clinical utility of liquid biopsy in breast cancer: A systematic review.Semantic proximity Read

Analysis of PIK3CA Mutations with Clinicopathological Features and Prognosis in Breast cancer patients with Undergoing Neoadjuvant TherapySemantic proximity Read

Circulating PIK3CA mutation detection at diagnosis in non-metastatic inflammatory breast cancer patients.Semantic proximity Read

Quality-Assured Analysis of PIK3CA Mutations in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Tissue.Semantic proximity Read

Impact of Germline Genetic Variations on Breast Cancer Prognosis: A Systematic Review and Meta-AnalysisSemantic proximity Read

Germline Genetic Variations and Breast Cancer Prognosis: A Systematic Review and Meta-AnalysisSemantic proximity Read