Article
The relevance of ultradeep sequencing for low HIV-1 viral loads and proviruses in the clinical setting.
Journal of medical virology - 1 Aug 2024
Foury Alizée, Saunier Aline, Taverniers Audrey, Pinet Nathalie, Josse Thomas, Jeanmaire Eliette, Emilie Caroline, Schvoerer Evelyne, Hartard Cédric
Abstract excerpt
Improving the therapeutic management of HIV-positive persons is a major public health issue and includes better detection of drug resistance mutations (DRMs). The aim of this study was (i) to explore DRMs in HIV-1-positive persons presenting a blood viral load (VL) < 1000 genomes copies (gc)/mL, including the analyze of cerebrospinal fluid (CSF) and HIV-DNA from peripheral blood mononuclear cells using ultradeep...
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