Article
Sanger and Next Generation Sequencing Approaches to Evaluate HIV-1 Virus in Blood Compartments.
International journal of environmental research and public health - 9 Aug 2018
Arias Andrea, López Pablo, Sánchez Raphael, Yamamura Yasuhiro, Rivera-Amill Vanessa
Abstract excerpt
The implementation of antiretroviral treatment combined with the monitoring of drug resistance mutations improves the quality of life of HIV-1 positive patients. The drug resistance mutation patterns and viral genotypes are currently analyzed by DNA sequencing of the virus in the plasma of patients. However, the virus compartmentalizes, and different T cell subsets may harbor distinct viral subsets. In this...
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