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Causality of Genetically Determined Metabolites and Metabolic Pathways on Osteoarthritis: A Bi-Directional Two-Sample Mendelian Randomization Study

2023-01-23

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<title>Abstract</title> <p>Background Osteoarthritis (OA) is one of the most prevalent musculoskeletal diseases, and is the leading cause of pain and disability in the aged population. However, the underlying biological mechanism has not been fully understood. This study aims to reveal the causal effect of circulation metabolites on OA susceptibility. Methods A bi-directional two-sample Mendelian Randomization...

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Literature Corpus work
a2f2c2fb-2fdb-5312-846f-0c265f3948be
DOI
10.21203/rs.3.rs-2378718/v1
Open publication

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Causality of Genetically Determined Metabolites and Metabolic Pathways on Osteoarthritis: A Bi-Directional Two-Sample Mendelian Randomization StudyDOI 10.21203/rs.3.rs-2378718/v1
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