Back to search

Article

Associations between IBS, IBD and the risk of Insomnia: An Observational Analysis and Genome-wide Interaction Study

2022-05-31

Abstract excerpt

<h4>Background: </h4> Irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) were reported to be associated with mental disorders. But limited efforts were made to investigate the relationship between IBS/IBD and the risk of insomnia, especially from genetic perspective. <h4>Methods: </h4>: Based on the UK Biobank cohort, we first calculated the polygenic risk scores (PRS) of IBS and IBD. Linear regr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
901fdf3f-56fc-5c1c-aa9b-e4c9ac8e8c67
DOI
10.21203/rs.3.rs-1695595/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Associations between IBS, IBD and the risk of Insomnia: An Observational Analysis and Genome-wide Interaction StudyDOI 10.21203/rs.3.rs-1695595/v1
Unraveling the genetic susceptibility of irritable bowel syndrome: integrative genome-wide analyses in 845 492 individuals: a diagnostic studySemantic proximity
Associations of sleep patterns, Metabolic Dysfunction, and Genetic Susceptibility With Incident Crohn’s Disease and Ulcerative Colitis: A Prospective Cohort StudySemantic proximity
Alleviating insomnia should decrease the risk of irritable bowel syndrome: Evidence from Mendelian randomizationSemantic proximity
Insomnia is associated with reduced quality of life in inflammatory bowel diseaseSemantic proximity
Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new genetic hitsSemantic proximity
Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants.Semantic proximity
Identifying the potential role of insomnia on multimorbidity: A Mendelian randomization phenome-wide association study in UK BiobankSemantic proximity
Identifying the potential causal role of insomnia symptoms on 11,409 health-related outcomes: a phenome-wide Mendelian randomisation analysis in UK Biobank.Semantic proximity
Evaluating the Effects of Diet-Gut Microbiota Interactions on Sleep Traits Using the UK Biobank Cohort.Semantic proximity
Lifestyle and genetic predisposition are associated with incident irritable bowel syndrome: A population-based prospective cohort study.Semantic proximity
Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease.Semantic proximity
Shared genetic susceptibilities for irritable bowel syndrome and depressive disorder in Chinese patients uncovered by pooled whole-exome sequencingSemantic proximity
Select a neighboring publication to make it the new centre.