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Article

L1CAM mediates neuroendocrine phenotype acquisition in prostate cancer cells.

The Prostate - 1 Dec 2024

Hsieh Chia-Ling, Do Anh Duy, Hsueh Chia-Yen, Raboshakga Mafewu Olga, Thanh Tran Ngoc, Tai Tran Tien, Kung Hsing-Jien, Sung Shian-Ying

Abstract excerpt

BACKGROUND: A specific type of prostate cancer (PC) that exhibits neuroendocrine (NE) differentiation is known as NEPC. NEPC has little to no response to androgen deprivation therapy and is associated with the development of metastatic castration-resistant PC (CRPC), which has an extremely poor prognosis. Our understanding of genetic drivers and activated pathways in NEPC is limited, which hinders precision...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neural Cell Adhesion Molecule L1

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Source

Identifiers

PMID: 39154281
DOI: 10.1002/pros.24782

Genes

L1CAM
PC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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