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Article

Neuroendocrine Prostate Cancer: Subtypes, Biology, and Clinical Outcomes

1 May 2014

Abstract excerpt

Neuroendocrine prostate cancer (NEPC) encompasses various clinical contexts, ranging from the de novo presentation of small cell prostatic carcinoma to a treatment-emergent transformed phenotype that arises from typical adenocarcinoma of the prostate. The development of resistance to potent androgen receptor signaling inhibition may be associated with the emergence of aggressive phenotype, advanced...

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PMID: 24812138
DOI: 10.6004/jnccn.2014.0073

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