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Article

The Many Faces of Neuroendocrine Differentiation in Prostate Cancer Progression

25 Mar 2014

Abstract excerpt

In normal prostate, neuroendocrine (NE) cells are rare and interspersed among the epithelium. These cells are believed to provide trophic signals to epithelial cell populations through the secretion of an abundance of neuropeptides that can diffuse to influence surrounding cells. In the setting of prostate cancer (PC), NE cells can also stimulate surrounding prostate adenocarcinoma cell growth, but in some cases...

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PMID: 24724054
DOI: 10.3389/fonc.2014.00060

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