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Article

Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate Adenocarcinoma

6 Feb 2020

Abstract excerpt

Neuroendocrine prostate cancer (NEPC) can arise de novo, but much more commonly occurs as a consequence of a selective pressure from androgen deprivation therapy or androgen receptor antagonists used for prostate cancer (PCa) treatment. The process is known as neuroendocrine transdifferentiation. There is little molecular characterization of NEPCs and consequently there is no standard treatment for this kind of...

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PMID: 32041153
DOI: 10.3390/ijms21031078

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