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Article

Molecular model for neuroendocrine prostate cancer progression

23 Mar 2018

Abstract excerpt

Prostate cancer (PCa) is the most common form of cancer in men in the developed world and the second leading cause of cancer-related deaths. While advanced PCa is initially controlled with hormonal therapies targeting the androgen receptor (AR) pathway, recurrence occurs because of the emergence of lethal castration-resistant PCa (CRPC). Despite newer AR pathway inhibitors that prolong survival, resistance still...

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PMID: 29569310
DOI: 10.1111/bju.14207

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