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Article

Dependence on MUC1-C in Progression of Neuroendocrine Prostate Cancer

13 Feb 2023

Abstract excerpt

Castration resistant prostate cancer (CRPC) is responsive to androgen receptor (AR) axis targeted agents; however, patients invariably relapse with resistant disease that often progresses to neuroendocrine prostate cancer (NEPC). Treatment-related NEPC (t-NEPC) is highly aggressive with limited therapeutic options and poor survival outcomes. The molecular basis for NEPC progression remains incompletely...

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PMID: 36835130
DOI: 10.3390/ijms24043719

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