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Article

Mendelian randomization of plasma lipidome, inflammatory proteome and heart failure.

ESC heart failure - 1 Dec 2024

Zheng Zequn, Tan Xuerui

Abstract excerpt

AIMS: Heart failure (HF) is a global health issue, with lipid metabolism and inflammation critically implicated in its progression. This study harnesses cutting-edge, expanded genetic information for lipid and inflammatory protein profiles, employing Mendelian randomization (MR) to uncover genetic risk factors for HF. METHODS: We assessed genetic susceptibility to HF across 179 lipidomes and 91 inflammatory...

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Identifiers

PMID: 39145416
DOI: 10.1002/ehf2.14997
PMCID: PMC11631237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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