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Article

Genetic Evidence Linking Inflammatory Cytokines and Blood Metabolites to Heart Failure Risk.

Cardiovascular therapeutics - 1 Jan 2026

Yao Yanbing, Tang Linghui, Zhou Peilin, Huang Feng, Zeng Zhiyu

Abstract excerpt

BACKGROUND: Heart failure (HF) is a critical condition characterized by the heart's inability to pump blood effectively, leading to significant morbidity and mortality. Inflammation and metabolic disturbances play key roles in its progression. This study is aimed at elucidating the causal relationships between inflammatory cytokines, metabolites, and HF using Mendelian randomization (MR). METHODS: A three-step,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42112763
DOI: 10.1155/cdr/6340671
PMCID: PMC13159094

Genes

FGF19
LIFR
PC
TNF
TNFSF12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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