Article
Circulating inflammatory cytokines and the risk of sepsis: a bidirectional mendelian randomization analysis.
BMC infectious diseases - 7 Aug 2024
Jiang Wen-Xi, Li Hui-Hua
Abstract excerpt
BACKGROUND: Sepsis is a life-threatening condition that is characterized by multiorgan dysfunction and caused by dysregulated cytokine networks, which are closely associated with sepsis progression and outcomes. However, currently available treatment strategies that target cytokines have failed. Thus, this study aimed to investigate the interplay between genetically predicted circulating concentrations of...
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