Article
Gut microbiota, circulating inflammatory proteins and sepsis: a bi-directional Mendelian randomization study.
Frontiers in cellular and infection microbiology - 1 Jan 2024
Li Zuming, Lin Liangcai, Kong Yunqi, Feng Jieni, Ren Xiaolei, Wang Yushi, Chen Xueru, Wu Siyi, Yang Rongyuan, Li Jiqiang, Liu Yuntao, Lu Yue, Chen Jiankun
Abstract excerpt
Background: Gut microbiota is closely related to the occurrence and development of sepsis. However, the causal effects between the gut microbiota and sepsis, and whether circulating inflammatory proteins act as mediators, remain unclear. Methods: Gut microbiota, circulating inflammatory proteins, and four sepsis-related outcomes were identified from large-scale genome wide association studies (GWAS) summary data....
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