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Article

Sex-Based Differences in Risk of Therapy-Related Myeloid Neoplasms.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Nov 2024

Richard Melissa A, Yan Chengcheng, Chen Yanjun, Gibson Christopher J, Kalra Rashi, Bosworth Alysia, Crossman David K, Singh Purnima, Hageman Lindsey, He Jianbo, Armenian Saro H, Vose Julie, Weisdorf Daniel J, Ebert Benjamin L, Yasui Yutaka, Cheng Changde, Forman Stephen J, Bhatia Smita, Bhatia Ravi

Abstract excerpt

PURPOSE: Therapy-related myeloid neoplasm (t-MN) is a life-threatening complication of autologous peripheral blood stem cell (PBSC) transplantation for non-Hodgkin lymphoma (NHL). Previous studies report an association between clonal hematopoiesis (CH) in PBSC and risk of t-MN, but small samples precluded examination of risk within specific subpopulations. METHODS: Targeted DNA sequencing was performed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39094067
DOI: 10.1200/JCO-24-01487
PMCID: PMC11521772

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