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Clonal Hematopoiesis and Myeloid Neoplasms in the Context of Telomere Biology Disorders.

Current hematologic malignancy reports - 1 Jun 2022

Ferrer Alejandro, Mangaonkar Abhishek A, Patnaik Mrinal M

Abstract excerpt

PURPOSE OF REVIEW: Telomere biology disorders (TBDs) are cancer-predisposing multisystemic diseases that portend a higher risk of transforming into myeloid neoplasms (MNs). Due to the rarity and high variability of clinical presentations, TBD-specific characteristics of MN and the mechanisms behind this predisposition are not well defined. Herein, we review recent studies on TBD patient cohorts describing myeloid...

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Biology
Clonal Hematopoiesis
Leukemia, Myeloid, Acute
Mutation
Myeloproliferative Disorders

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PMID: 35524933
DOI: 10.1007/s11899-022-00662-8
PMCID: PMC9077347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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